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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e22e88b1aae8d8dce9ccb6517561fa83788a28acfd2b6b26efbad9e5cb453a' 
  AND token = 'YMpigb/5iZTPT60HZdPnG7ogjcmGkGhj27HXPl6RbYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}