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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1224e41d979a00efb102ef48348c38f42e00fe46380d3661329a352d5aedac51' 
  AND token = '9g1RVU3H9g8MuVci22BLwlHeW1BExOMP/Irt2hVczZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}