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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f25d0cffd5a932c91125609a8c0a05a888474835d166fa14c32a663bf6659c4' 
  AND token = 'FC2Ey3SE3/1iTRHlllMjjoEew+qn80xQM5UWutacIJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}