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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4ce1daf70fa846c887be23f0ad75ea448be8b15d6ff6310e371f6f21df9c1bd' 
  AND token = 'OwNSfm+s8LLvdIRlkJWYmPI4hp3icF/a+5kdU4IC+yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}