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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8349d27a503b843925142534eb8ff8cd7f777353e53f8e783456015be5cd992d' 
  AND token = 'PrAl5xL2lOq0xu2GmNv6SkWtj+PbJ4luUdRmTDWLKLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}