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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72049ee65f7105d44ec0f9a85942d17166841226b6afa3ae5de99542261791df' 
  AND token = 'jE+QHBJbIRgTD2idz15WH4RIc6A6toDJg4+U34hUnS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}