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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5ec4ccfad0a841ec70c58b3701c2052a22cc0921fdc156a2d98b2f80e329712' 
  AND token = 'p0UdomLwMR5sFV58tsEqUmftNGofrnyZw5VLx2TneFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}