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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc3ef2f10aa909f26117a25d18cbc90b0b9a3de257478ae82f921d5493a35d61' 
  AND token = 'hhDJc2ZPY10j/iCZDgjdNxfc80K6Cv2DZZMN627Reyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}