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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54e0cddc93c0146e568914a7572067e1fa91abf2a5e0aa64d7bab7fd2b860600' 
  AND token = 'DFcuKV8KwgczxUblZ8kJmR99VDGXX9v7oO5wb0KpSR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}