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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4139743833dd800524751bd0e8ac4bc2681359d3dff97e167908aca8d8ad3141' 
  AND token = 'V01+J0WZsqfzHy/LJ94xlH66a+oXt5jW8ZhjDzI8RHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}