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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9147a93aa60471bf71dcac3bda978f01024b1b2f9bef88ee48a23f903f0f64b0' 
  AND token = 'GY+51FcbHeOeHTG1LUjL9vP6Qy6F5mmFSKwXkLz5xJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}