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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c3a0ae08986cac62a33e9ffa6c8fe39f743956f672e9fadd6c432aa2d49d785' 
  AND token = 'uZ0iILP14/I6SaBNgZF0SAYJOF7zWv1UYs+UXPn1EHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}