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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09b920f5e75b2041cb4d425209a40298b0ddf66adc879a3351c61a61122afc14' 
  AND token = 'V1x6swaAhMKUsX1qKLSWMHKdtuWBZaQZvAJ4aN95HB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}