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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1687dbb43fc51732de48690ee298ce619b455929ff1163de1aff4f8045f1bf00' 
  AND token = 'yt3oeFNu0M/pP6S5t3f7SK4okCy+6e47mRUMsL3nfK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}