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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ec2bfad4cd0c350d6136c1ea2bf6edffd5e481776968eb747907eef60c0319f' 
  AND token = 'iyDdd0YyO+AhmHrhZ3uNIga56jlOZir3hV4oy75inaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}