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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22833b528e0ed8af4a047997c64fabc17ff02e814d9c750a1b1503258510191b' 
  AND token = 'VcBfo075elp0umBtJ2FTrYiy2u1EkyAbCBuidhVhEU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}