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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '798850251a3f8cca71b7afbd262ca864afb910cd58a620f8e1b5be4f08bcac49' 
  AND token = 'Wn5h1/1JqxExkh2be1+i2E4E84RQ323Mrw8gVc3Lbpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}