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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36cfca0f3a728aefd0db84db76d87f937c7f603416ca6b544e91d7f85033b11a' 
  AND token = 'pS81hyybrA3yI60wdWGRU/71s+EKtiZlQNF3vorxSS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}