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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aae889db81b0fb74a63e372c2c4954edaf256e87f810e8b1f6da60c2d32083d' 
  AND token = 'JZtkMMa5dbQvQAm7nyctOdQA1MPbc3D693MzZkLKqxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}