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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca2de167c3d27d2a8e59aa9f10393ae35c9a7435c0d781e939113fa60bc63b8f' 
  AND token = 'gATq2cMGVSVgX+DQDRqHmHGTPBiT0XDy7DZLVG8mRx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}