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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05bddec4aaaedac46115d63cccb660d371e1a0906bbbd2c5ff7a9387d321a794' 
  AND token = 'dV7aPlvL8uJYjNT3khuKU3eu/NvuJa0RwaqZS9HCXQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}