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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c10b417c79b827dbe139c7ed8902afadb4e252acebe286ff9b554568ad26fc7' 
  AND token = 'l4v9F/MLeEocZH9N3UWdLMMMgC2XZz983kr2Uwse4Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}