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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1473d89cae7a24729f3935434a2f10de3b34be5931e55e83dc36dd048cc41b14' 
  AND token = 'ndOqo0G2vxcy0tzkyknxMXobRamUBjgzu99NXC5M/0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}