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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a42ca194eb463e2dbeb8ecc0d7ad8b564d7a106c768d445d6dfca9e97fd503c' 
  AND token = 'CzSJbV66Q006PmmZd8qY8IfMYoaLKeEiOYOzP0OkE/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}