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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2f809ad566b0e102bfa88f159fa5bd270980f0308df126810d52e1a980432b' 
  AND token = 'V8x65fzgwrXwZGkuEm61BhoshmPAtX5QfRFWJm2NlnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}