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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a9a385abc7b98cc6838ce7950627b8851b216e732a12933f1cc1bdbcc3d7abc' 
  AND token = 'SbyvymzzcMqPVd9aXctn1XuszZiwoIxC7gJFz28R/Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}