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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a412bc4b6da8577cae7d9064f04c7d658f92844a3c224ca1c11f96ea866671c' 
  AND token = 'jlEsUt0cfjK2Mj8afpuTWLQUjx6t2CYrK8KezZ/rzik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}