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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561963c568af7eaa922bbbc272eb2916a155befaffd70b2f20d381ced2ec838f' 
  AND token = 'HkHOX+v+gS7jRgeSmYswm/J3B5dad+BHmIRT20c+rrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}