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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8c5795b1f50c2f8d89b293bd221293810f4803dda8a4eeff69e2d6d2c77193' 
  AND token = 'Av2Iw3uG7VSHUr9k5EaWvIvynjrtFKy23+5sZG7usaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}