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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc121d6e9ad2a11c23f8db71f22fd64d240714b4ea47bf079cf1b2cade697e3' 
  AND token = '6lEWWfy4oTe5pph67dXc+FwQ89fDRe8YwyNw4XXvoLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}