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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5eb3e0209a4b0f9a68d195d916b941ba0821d9bf97dec65791fa3092cb02c5' 
  AND token = 'tYGUjwyM/6d/6UFYY+xiYI+grGNXnRHLakViu2IvXHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}