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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ff430c8f5f9a7e4b90a8888dc16d3031d053e5e7b39ce9891c559b4ab7b448' 
  AND token = 'R+d8fnkoUtv8RRmVmhOSIS+PH7VcPjHepiH/f+UROaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}