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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0d13e5a96a98e4b8c86db62a84f7d13a4961b8f4653c3b913951e104e6a253' 
  AND token = 'DMCd82pubblRWjxh+5UzZVacYzdAbURPBu2mrHRl508=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}