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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d1e8b955e3c627eee943ea42834da90222e2cd7b748b36dcad21a40e4276de' 
  AND token = 'pcd19WFiftq6Jd9DGr9p1BWIht63ZE3EEHgbYA2rE4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}