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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42d5869a3e981d80a3c800556d14567868a2de789d7cd4a9c40fb2bef47cad5b' 
  AND token = 'ejD8aA0QvbdMwlgPt6G33SW43+h5pH5BDXT4v6SGbNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}