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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f80293a7ef53201e9e26f39b26f13fa4283d23fccb12dcd9e132a8a7de447a6' 
  AND token = 'hvHFJ/d94+sB8OBWui+UXupTLdRJIBQRNg8ys6wDfpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}