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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b60eebc1299a837c0c83b8e7bd9f6ada97c37aeff8262af4420aab0725849bc1' 
  AND token = 'R9EuRSUi3+8HEC0V43Ltbn3Aty4J4hlqsgcx1jKFrwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}