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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e225528977902ecd6b6b13eed5551372d223a7ce4c20f1e4bf3ef806cb5d7ae8' 
  AND token = 'sJzycUb4jDjHuzXEbswBwbKj/tmNFEKZSdtK0Lb4PXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}