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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d1e70a3ce5a194983a51bb37650eea44ac4c86261ef77d1e18808fed6259d76' 
  AND token = 'DZMeBVdyHMgKayImW9vos0iMWG/m+2ik/6oddDX4e7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}