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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cbb8141379e124a9b24256e3c4b4355cd9266377ca466fd0346c7f30f33f10f' 
  AND token = 'hR8Q3s9z5vIWAkiVtzbNeJ9ffD78aeT9AlgniRdjdW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}