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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a068e2497b3eca2a647963810b8d2e3aa239dba61b11d9706517e323adf120' 
  AND token = 'AM2s3a1/vWIRfZX4bc+WQneKN1Ab0/dVhbQt9dbcTaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}