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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecfaf744fca5e86559c8a847e1288b3127ef880a2816f79a304f5814d49d6a68' 
  AND token = 'epuTwg1KO5RNefcoaTpHaFx9r/jt4e/+BWTqYL6R03w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}