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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55271aede76e8be43f16456feb04dcde2e8b3ab8beb35d5ae2076921f2931972' 
  AND token = 'yvGXjCeoDI7Q+TgisCoqlPWOMVPqqCZT7X2F/xCTkXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}