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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e1f0825e50e189ec060a550db53233b40dfafa327ef724bbc6bce2f586bf78' 
  AND token = 'Z3f3oBISTaa8GQqVCW8g3SN4+3OIw8ykOlHU3SVKd14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}