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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bfd8e2d4207e2a224013588f39f2e00857d345cf6402ac10c5be352bef74ecf' 
  AND token = 'HcUUfFGpUFlyYtaftn1Z5kr9Jy+rQCuR5a2zjMR0Gqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}