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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5787aefadc911fcb30d1f2c2bef505c809e2807f55e5b9f230459eed7882c6ad' 
  AND token = 'pdUm1pjx5h7fuW7EPHM1rx0eE6GXzpJ94rBP7aGUYzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}