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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3edaa42157e7156a834c9b9035dd3ec0024c6f98a45b94d29a34b2c7b5f52a7f' 
  AND token = '+x1IpzRbunIYXY4Nd36y0mrvme/VymZV8UbuU+PqXf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}