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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12368f8f6d610ab18c659049f30b433024acad4d8d69cb3b18f864ca387b8ced' 
  AND token = 'rUyaQ9AaVw7//jjR3dwCZUuHpe7dHgYGiYKwr7T4sDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}