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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6df67aefc002630f0bfe973018a6688741e46c9725bf60653663a349f6072eaf' 
  AND token = 'l84kpgr/1C1myo4hMkq1GWENdwy/gusye+0A5x3nDsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}