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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f0b8fbf7f102408da1c03c59d60c5551f8753dc28c85392768742f29791bdc' 
  AND token = 'tUIJEubiND8Ai/rbFpXkILKGb+eIA9twhjFpP/9t6Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}